Recent advances in hemorrhage transformation and clinical prognoses after intravenous thrombolysis in acute ischemic stroke with cerebral small vessel disease
10.3760/cma.j.issn.1671-8925.2019.05.009
- VernacularTitle:合并脑小血管病的急性缺血性脑卒中患者静脉溶栓后出血转化及临床预后的研究进展
- Author:
Xueyun LIU
1
;
Tan LI
;
Chunhao MEI
;
Lulu ZHANG
;
Yun ZHOU
;
Shanshan DIAO
;
Qi FANG
Author Information
1. 苏州大学附属第一医院神经内科
- Keywords:
Acute ischemic stroke;
Cerebral small vessel disease;
Intravenous thrombolysis;
Hemorrhagic transformation;
Clinical prognosis
- From:
Chinese Journal of Neuromedicine
2019;18(5):481-486
- CountryChina
- Language:Chinese
-
Abstract:
The development of neuroimaging has led to a high diagnostic rate of cerebral small vessel disease (CSVD).The hemorrhage transformation (HT) and clinical prognosis after intravenous thrombolysis in acute ischemic stroke (AIS) with CSVD have become hot topics in recent years.Relevant studies have shown that different subtypes of CSVD may have different influences in HT and clinical prognoses in AIS.In clinic,each subtype of CSVD may not exist alone in one patient,therefore,some scholars put forward the concept of total burden of CSVD to further quantitatively assess the severity of CSVD in the whole brain and their effects on HT and clinical prognosis after intravenous thrombolysis of AIS.This article reviews the researches on HT and clinical prognosis after intravenous thrombolysis in AIS with CSVD.
