Pathogenesis of neuromyelitis optica spectrum disorder
	    		
		   		
		   			
		   		
	    	
    	 
    	10.3760/cma.j.issn.1671-8925.2017.11.022
   		
        
        	
        		- VernacularTitle:视神经脊髓炎谱系疾病的发病机制研究进展
 
        	
        	
        	
        		- Author:
	        		
		        		
		        		
			        		Lingling LI
			        		
			        		
			        		
			        			1
			        			
			        		
			        		
			        		
			        		
			        		;
		        		
		        		
		        		
			        		Xiujuan SONG
			        		
			        		;
		        		
		        		
		        		
			        		Guojun TAN
			        		
			        		;
		        		
		        		
		        		
			        		Huiqing HOU
			        		
			        		;
		        		
		        		
		        		
			        		Bin LI
			        		
			        		;
		        		
		        		
		        		
			        		Huijia LIU
			        		
			        		;
		        		
		        		
		        		
			        		Xiaohong DENG
			        		
			        		;
		        		
		        		
		        		
			        		Beiping WANG
			        		
			        		;
		        		
		        		
		        		
			        		Meng CUI
			        		
			        		
		        		
		        		
		        		
		        		
		        			
			        		
			        		Author Information
			        		
		        		
		        		
			        		
			        		
			        			1. 050000石家庄,河北省神经病学重点实验室,河北医科大学第二医院神经内科
			        		
		        		
	        		
        		 
        	
        	
        	
        	
        		- Keywords:
        			
	        			
	        				
	        				
			        		
				        		Neuromyelitis optica spectrum disorder;
			        		
			        		
			        		
				        		Pathogenesis;
			        		
			        		
			        		
				        		Gene;
			        		
			        		
			        		
				        		Environment;
			        		
			        		
			        		
				        		Oxidative stress
			        		
			        		
	        			
        			
        		
 
        	
            
            
            	- From:
	            		
	            			Chinese Journal of Neuromedicine
	            		
	            		 2017;16(11):1184-1188
	            	
            	
 
            
            
            	- CountryChina
 
            
            
            	- Language:Chinese
 
            
            
            	- 
		        	Abstract:
			       	
			       		
				        
				        	Neuromyelitis optica spectrum disorder (NMOSD) is a kind of immune mediated inflammatory demyelinating disease of the central nervous system manifesting with optic neuritis and acute transverse myelitis,which takes a relapsing or progression course.The exact etiology and pathogenesis are not clear.There are a lot of researches on immune pathogenesis;in addition,the pathogenesis also involves genetic,environmental,oxidative stress and other factors.