Research progress of probes labeling with radionuclide for early apoptosis imaging
10.3760/cma.j.issn.1671-8925.2016.03.021
- VernacularTitle:放射性核素标记的早期凋亡显像探针研究进展
- Author:
Shiming HUANG
1
;
Zhichun LIN
;
Lijun CHEN
Author Information
1. 天津武警后勤学院附属医院核医学科
- Keywords:
Apoptosis;
Radionuclide imaging;
Annexin V;
Caspases
- From:
Chinese Journal of Neuromedicine
2016;15(3):310-314
- CountryChina
- Language:Chinese
-
Abstract:
Assessment of cell apoptosis may help for an early and exact diagnosis of some diseases,and provide important evidence for therapy and its results.As a safe,noninvasive and real-time imaging means of the highest level in nuclear medicine,positron emission tomography (PET) can use apoptotic PET tracer to detect cell apoptosis.The exploitation of suitable probes is important for PET to detect early cell apoptosis.According to various biochemical changes of apoptotic cells,there are already quite an amount apoptosis imaging probes have been investigated.This review mainly introduces PET apoptosis imaging probes and their latest application.
