Prognosis of intracranial aneurysms after microsurgical treatment and risk of cerebral vasospasm: a relevant factor analysis
10.3760/cma.j.issn.1671-8925.2011.07.014
- VernacularTitle:显微手术治疗颅内动脉瘤后脑血管痉挛和预后的影响因素分析
- Author:
Guo-Dong HUANG
1
;
Wei-Pin LI
;
You-Zeng FU
;
Tao JI
;
Yong-Zhong GAO
Author Information
1. 深圳大学第一附属医院(深圳市第二人民医院)
- Keywords:
Intracranial aneurysm;
Subarachnoid hemorrhage;
Microsurgery;
Cerebral vasospasm;
Prognosis
- From:
Chinese Journal of Neuromedicine
2011;10(7):705-708
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the relevant factors of prognosis of intracranial aneurysms after microsurgical treatment and risk factors of cerebral vasospasm (CVS). Methods Three hundred and twenty-two patients with intracranial aneurysms, admitted to and received surgical treatment in our hospital from June 2006 to May 2009, were chosen in our study; their clinical data were retrospectively analyzed. Logistic regression analysis was employed to analyze the influences of age, gender, blood pressure level, blood sugar level, operation time, Fisher's grade, Hunt Hess grade and infection on the prognosis of patients with intracranial aneurysms and the risk of CVS. Results Multivariate logistic analysis indicated that age, Hunt Hess grade, Fisher's grade, CVS, infection and lumber puncture times were the independent risk factors influencing the prognosis of patients with intracranial aneurysms (P< 0.05). Hunt Hess grade, Fisher's grade, number of aneurysms, endplate colostomy, lumber puncture times and infection were the independent risk factors of CVS (P<0.05). Conclusion Age, Hunt Hess grade, Fisher' s grade, CVS, lumber puncture times and infection are the independent risk factors affecting the prognosis of patients with intracranial aneurysms, among which, CVS is the most important factor. CVS is mainly affected by Hunt Hess grade, Fisher's grade, number of aneurysms, endplate colostomy, lumber puncture times and infection.
