Risk factors and predictive models for liver cancer after sustained virologic response in hepatitis C
- VernacularTitle:丙型肝炎持续病毒学应答后肝癌发生的危险因素及预测模型
- Author:
Shanshan XU
1
;
Lixia QIU
;
Yali LIU
;
Jing ZHANG
Author Information
- Keywords: Hepatitis C; Sustained Virologic Response; Liver Neoplasms; Risk Factors
- From: Journal of Clinical Hepatology 2024;40(6):1259-1263
- CountryChina
- Language:Chinese
- Abstract: Hepatitis C is one of the main causes of liver cancer.With the application of direct-acting antiviral agents,more than 95%of patients can achieve the eradication of hepatitis C virus and obtain sustained virologic response(SVR).Effective antiviral therapy can change the natural course of hepatitis C and reduce the risk of liver cancer;however,some patients are still affected by age,sex,liver fibrosis,diabetes,hepatic steatosis,alcohol consumption,and genetic factors and become the high-risk population of liver cancer.Therefore,it is needed to further clarify and improve the identification and prediction of high-risk populations of liver cancer after SVR of hepatitis C.This article reviews the risk factors and predictive models for liver cancer after SVR in patients with hepatitis C,in order to provide a basis for identifying the high-risk population of liver cancer after SVR of hepatitis C in clinical practice.
