Multimodality imaging and specific targeting probes for primary liver cancer
10.3781/j.issn.1000-7431.2023.2304-0180
- VernacularTitle:原发性肝癌多模式生物成像及特异性靶向探针
- Author:
Chihua FANG
1
;
Xingyang ZHAO
Author Information
1. 南方医科大学珠江医院肝胆一科,广东广州 510280;广东省数字医学临床工程技术研究中心,广东广州 510280
- Keywords:
Primary liver cancer;
Multimodality imaging;
Specific targeting probe
- From:
Tumor
2023;43(6):525-533
- CountryChina
- Language:Chinese
-
Abstract:
Primary liver cancer(PLC)is one of the most common malignant diseases with the highest incidence and mortality rate,which poses a serious threat to public health in China.Thus,it is crucial to realize the early and accurate diagnosis of PLC.In clinical practice,traditional imaging techniques can provide the morphological information of liver cancer tissues,but they still have some limitations.Multimodality imaging can provide more comprehensive diagnostic information by integrating the advantages of different imaging technologies.By using liver cancer-specific targeting probes,multimodality imaging technology can achieve higher sensitivity and specificity than traditional imaging techniques.It can not only help with the accurate diagnosis of liver cancer by providing the structural and functional information of PLC simultaneously,but also guide surgeons to make better intraoperative decisions for PLC patients by supporting real-time navigation imaging during surgery.Therefore,multimodality imaging is of great significance to the clinical diagnosis and treatment of PLC.This review mainly focuses on the multimodality imaging technology and specific targeting probes of PLC,and summarizes the current research progress in this field.