Multiomics research on stroke and its potential significance
10.3760/cma.j.cn114452-20231009-00194
- VernacularTitle:脑卒中多组学研究及其潜在意义
- Author:
Xiaomin ZHANG
1
;
Peichang WANG
Author Information
1. 首都医科大学宣武医院检验科，北京100053
- Keywords:
Stroke;
Biomarkers;
Genomics;
Transcriptomics;
Proteomics;
Metabolomics
- From:
Chinese Journal of Laboratory Medicine
2024;47(2):111-115
- CountryChina
- Language:Chinese
-
Abstract:
Stroke is an acute cerebrovascular disease, and a group of diseases that cause brain tissue damage due to sudden rupture of brain blood vessels or blockage of blood vessels, mainly including ischemic stroke and hemorrhagic stroke. In recent years, although some progresses have been achieved, there are still few biomarkers that can be used for effective warning and monitoring for people at high risk of stroke. Omics research is an important research strategy for discovering differential genes, molecules, and epigenetic markers in the process of disease occurrence and development. A systematic summary of progress made in recent years, in stroke genomics, transcriptomics, proteomics, and metabolomics in recent years, as well as their potential applications in stroke warning, diagnosis, and monitoring, was systematically discussed in the presence review, in order to provide reference for future research on stroke biomarkers.
