Update of international guidelines leads the clinical diagnosis and treatment of hematological malignancies into the era of precision medicine and genomics
	    		
		   		
		   			
		   		
	    	
    	 
    	10.3760/cma.j.cn114452-20230511-00241
   		
        
        	
        		- VernacularTitle:国际指南更新引领血液肿瘤临床诊疗进入精准医学和基因组时代
 
        	
        	
        	
        		- Author:
	        		
		        		
		        		
			        		Fang WANG
			        		
			        		
			        		
			        			1
			        			
			        		
			        		
			        		
			        		
			        		;
		        		
		        		
		        		
			        		Xue CHEN
			        		
			        		;
		        		
		        		
		        		
			        		Qisheng WU
			        		
			        		;
		        		
		        		
		        		
			        		Yang ZHANG
			        		
			        		;
		        		
		        		
		        		
			        		Hongxing LIU
			        		
			        		
		        		
		        		
		        		
		        		
		        			
			        		
			        		Author Information
			        		
		        		
		        		
			        		
			        		
			        			1. 河北燕达陆道培医院检验医学科,廊坊 065201
			        		
		        		
	        		
        		 
        	
        	
        	
        	
        		- Keywords:
        			
	        			
	        				
	        				
			        		
				        		Hematologic neoplasms;
			        		
			        		
			        		
				        		Leukemia;
			        		
			        		
			        		
				        		Genes;
			        		
			        		
			        		
				        		Mutation;
			        		
			        		
			        		
				        		Gene fusion;
			        		
			        		
			        		
				        		High-throughput nucleotide sequencing
			        		
			        		
	        			
        			
        		
 
        	
            
            
            	- From:
	            		
	            			Chinese Journal of Laboratory Medicine
	            		
	            		 2023;46(9):888-892
	            	
            	
 
            
            
            	- CountryChina
 
            
            
            	- Language:Chinese
 
            
            
            	- 
		        	Abstract:
			       	
			       		
				        
				        	As medical research progresses, an increasing number of genetic variations are being incorporated into international guidelines for the diagnosis and treatment of hematological malignancies. In several international guidelines updated in 2022, more emphasis is placed on the importance of genetic variation in the classification and prognosis assessment of hematological malignancies. The clinical diagnosis and treatment of hematological malignancies have entered the era of precision medicine and genomics, relying increasingly on the application of high-throughput sequencing technology.