Comparison of immune responses and protective efficacy between mucosal vaccines and intramuscular vaccines
10.3760/cma.j.cn112309-20230204-00019
- VernacularTitle:黏膜疫苗和肌肉注射疫苗免疫应答特征及免疫效果比较
- Author:
Hongyan LIN
1
;
Chunlan ZHUANG
;
Tingquan ZHENG
;
Ting WU
Author Information
1. 厦门大学公共卫生学院，国家传染病诊断试剂与疫苗工程技术研究中心，分子疫苗学和分子诊断学国家重点实验室，厦门 361102
- Keywords:
Mucosal vaccine;
Intramuscular vaccine;
Immune response
- From:
Chinese Journal of Microbiology and Immunology
2023;43(11):893-900
- CountryChina
- Language:Chinese
-
Abstract:
The routes of immunization largely determine the features of vaccine-induced immune responses. This paper mainly reviewed the immune responses and protective efficacy induced by mucosal immunization and intramuscular injection of vaccines against poliovirus, Salmonella typhi, influenza virus and SARS-CoV-2 and compared the differences between different immunization routes, with the goal of providing some fundamental theoretical data for the development of vaccines and vaccination strategies against infectious diseases.
