Phenytoin induced chorea: a case report and literature review

VernacularTitle:苯妥英导致的舞蹈病1例并文献复习
Author: Shuning DU ¹ ; Yang LI ; Xinyao LI ; Yuling TIAN ; Qiuyan WANG
Author Information

1. 山西医科大学第一医院神经内科，太原　030001
Keywords: Phenytoin; Drug side effects; Chorea
From: Chinese Journal of Neurology 2023;56(11):1290-1293
CountryChina
Language:Chinese
Abstract: Chorea is a rare adverse effect of phenytoin and is common in children, with widely variable clinical presentations. This article reported a case of an elderly woman presented chorea without nystagmus, ataxia, dysarthria and other typical vestibular-cerebellar symptoms, who took compound theophylline and ephedrine contained phenytoin to treat asthma for 1 year. The serum phenytoin concentrations were at toxic levels and chorea disappeared within 3 days after discontinuation of the drug. The clinical features of previously reported cases of phenytoin-induced chorea were also summarized.