Causes analysis and treatment experience of early postoperative death after lobar lung transplantation in adults
10.3760/cma.j.cn421203-20230316-00055
- VernacularTitle:成人肺叶移植术后早期死亡原因分析及诊疗经验
- Author:
Mengyang LIU
1
;
Xuan LI
;
Guilin PENG
;
Chao YANG
;
Bing WEI
;
Xin XU
Author Information
1. 广州医科大学附属第一医院器官移植科 广州呼吸健康研究院，广州 510163
- Keywords:
Lobar lung transplantation;
Risk factor;
Adult
- From:
Chinese Journal of Organ Transplantation
2023;44(11):662-667
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the causes of postoperative mortality within 3 months after lobar lung transplantation and summarize the institutional experiences of diagnosis and treatment so as to improve its early survival rate.Methods:From January 2016 to December 2022, 7 adults underwent lobar lung transplantation and died within 3 months post-lung transplantation at First Affiliated Hospital of Guangzhou Medical University.Age, gender, preoperative status, reasons of lobar lung transplantation, surgical approaches, postoperative managements and major causes of death were summarized.Results:The 3-month postoperative mortality rate was 15.6%.Seven of them died within 3 months.There were 5 males and 2 females with a mean age of 63(49-72)year.Preoperatively 5 recipients stayed in a stable condition and 2 cases were critical with mechanical ventilation.Single lobar LT plus contralateral lung transplantation(4 cases), bilateral lobar LT(2 cases)and unilateral lobar lung transplantation(1 case)were performed.Lobar resection was due to pneumonia of donor lung(5 cases)and size mismatch(2 cases). Cause of mortality was pneumonia(3 cases), bronchial stump fistula(2 cases), kidney failure(1 case) and cardiac failure(1 case).Conclusions:Early 3 months mortality remains high after adult lobar lung transplantation.All risk factors should be comprehensively considered for lowering early mortality.
