Role of ion channels in the pathogenesis of rosacea
- VernacularTitle:离子通道与玫瑰痤疮发病机制的研究进展
- Author:
Ziyu WEI
1
;
Yong YANG
Author Information
- Keywords: Rosacea; Transient receptor potential ion channel; Voltage-gated sodium channel; Neuropeptides; Neurovascular; Neurogenic inflammation; Claudin
- From: Chinese Journal of Dermatology 2024;57(2):174-177
- CountryChina
- Language:Chinese
- Abstract: External physicochemical factors and emotional changes often lead to intermittent facial flushing in patients with rosacea, accompanied by burning, stinging, and itching sensations. Many studies have demonstrated that neurovascular dysfunction and neurogenic inflammation induced by neuropeptides released following the activation of ion channels were associated with the occurrence of rosacea. This review summarizes research progress on the role of ion channels in the pathogenesis of rosacea and provides evidence for further research on ion channels as potential therapeutic targets for rosacea.
