Research progress of near-infrared Ⅱ fluorescence imaging in the diagnosis and treatment of tumors
10.3760/cma.j.cn321828-20221019-00314
- VernacularTitle:近红外二区荧光成像在肿瘤诊疗中的研究进展
- Author:
Bin GUI
1
;
Nan JIANG
;
Qing DENG
Author Information
1. 武汉大学人民医院超声影像科，武汉 430060
- Keywords:
Neoplasms;
Optical imaging;
Fluorescence;
Trends
- From:
Chinese Journal of Nuclear Medicine and Molecular Imaging
2024;44(2):120-123
- CountryChina
- Language:Chinese
-
Abstract:
Near-infrared (NIR) can be divided into NIR-Ⅰ (650-900 nm) and NIR-Ⅱ (900-1 700 nm) according to its wavelength. Compared with traditional NIR-Ⅰfluorescence imaging, NIR-Ⅱ fluorescence imaging has lower tissue absorption and photon scattering as well as higher tissue penetration and resolution, which is considered as the most promising optical imaging technique in clinical application. In addition, combined with multimodal or therapeutic integrated molecular probes, NIR-Ⅱ fluorescence imaging can accurately localize tumors and guide treatment, providing a remarkable modality for early diagnosis and treatment of tumors. In this review, research progress on NIR-Ⅱ fluorescence imaging in the diagnosis, monitoring of metastasis and treatment of tumors are mainly introduced.
