Clinical research progress in boron neutron capture therapy for glioma

VernacularTitle:硼中子俘获疗法治疗脑胶质瘤的临床研究进展
Author: Fengxia LUO ¹ ; Yanping WU ; Yuemin LI
Author Information

1. 解放军总医院第八医学中心放疗科，北京　100091
Keywords: Boron neutron capture therapy; Glioma; Boron carrier; Radiotherapy
From: Chinese Journal of Radiation Oncology 2024;33(2):168-172
CountryChina
Language:Chinese
Abstract: Boron neutron capture therapy (BNCT) is an emerging treatment modality. BNCT is performed by injecting patients with the boron containing drugs, which has strong affinity with cancer cells. After undergoing irradiation with neutrons, the boron containing drugs can yield alpha and lithium particles, which can kill tumor cells precisely. To date, clinical studies of BNCT have been conducted in a variety of tumors, including glioblastoma multiforme, meningioma, head and neck cancer, sarcoma, malignant skin tumor, malignant melanoma and recurrent cancers, etc. With continuous construction of BNCT treatment centers around the world, this new technology will be quickly and comprehensively spread. In this article, clinical research progress in the application of BNCT for glioma treatment was reviewed.