Diagnostic analysis of primary hepatic lymphoepithelioma-like carcinoma on contrast-enhanced ultrasound
	    		
		   		
		   			
		   		
	    	
    	 
    	10.3760/cma.j.cn131148-20230630-00357
   		
        
        	
        		- VernacularTitle:肝脏淋巴上皮瘤样癌的超声造影诊断分析
 
        	
        	
        	
        		- Author:
	        		
		        		
		        		
			        		Hong QIN
			        		
			        		
			        		
			        			1
			        			
			        		
			        		
			        		
			        		
			        		;
		        		
		        		
		        		
			        		Qiannan ZHAO
			        		
			        		;
		        		
		        		
		        		
			        		Kun WANG
			        		
			        		;
		        		
		        		
		        		
			        		Kai YUAN
			        		
			        		;
		        		
		        		
		        		
			        		Xiaolong ZHANG
			        		
			        		;
		        		
		        		
		        		
			        		Yi DONG
			        		
			        		;
		        		
		        		
		        		
			        		Wenping WANG
			        		
			        		
		        		
		        		
		        		
		        		
		        			
			        		
			        		Author Information
			        		
		        		
		        		
			        		
			        		
			        			1. 复旦大学附属中山医院超声科,上海 200032
			        		
		        		
	        		
        		 
        	
        	
        	
        	
        		- Keywords:
        			
	        			
	        				
	        				
			        		
				        		Contrast-enhanced ultrasound;
			        		
			        		
			        		
				        		Liver neoplasms;
			        		
			        		
			        		
				        		Lymphoepithelioma-like carcinoma
			        		
			        		
	        			
        			
        		
 
        	
            
            
            	- From:
	            		
	            			Chinese Journal of Ultrasonography
	            		
	            		 2023;32(10):852-857
	            	
            	
 
            
            
            	- CountryChina
 
            
            
            	- Language:Chinese
 
            
            
            	- 
		        	Abstract:
			       	
			       		
				        
				        	Objective:To retrospectively analyze the contrast-enhanced ultrasound(CEUS) features of primary hepatic lymphoepithelioma-like carcinoma (LELC) and investigate the value of CEUS in the diagnosis of hepatic LELC.Methods:The images of CEUS of 12 cases with hepatic LELC were retrospectively analyzed. The perfusion patterns and time of enhancement were observed.Results:During the arterial phase, 11 lesions showed diffuse enhancement, while 1 lesion showed rim-like enhancement. The mean time of begin enhancement, time to peak, time to iso-enhancement and slightly hypo-enhancement were (17.92±5.81)s, (24.50±5.52)s, (29.55±6.25)s, (45.50±25.15)s, respectively. Compared with adjacent liver parenchyma, rapid enhancement was observed in 11 lesions and synchronous enhancement was observed in 1 lesion.As to time of peak enhancement, hyper-enhancement and iso-enhancement were observed in 11 lesions and 1 lesion, respectively. In portal phase, 8 lesions manifested slight hypo-enhancement, 3 lesions with marked hypo-enhancement and 1 lesion with iso-enhancement.And in delayed phase, 10 lesions showed marked hypo-enhancement and 1 lesion with slight hypo-enhancement. Ten lesions showed peripheral hyper-enhancement like a bright ring in the portal and delayed phase.Conclusions:CEUS is valuable for the diagnosis and differential diagnosis of hepatic LELC.