Human Immunodeficiency Virus (HIV) and Hepatitis Virus Coinfection among HIV-Infected Korean Patients: The Korea HIV/AIDS Cohort Study.
- Author:
Yong Chan KIM
1
;
Jin Young AHN
;
June Myung KIM
;
Youn Jeong KIM
;
Dae Won PARK
;
Young Kyung YOON
;
Joon Young SONG
;
Shin Woo KIM
;
Jin Soo LEE
;
Bo Youl CHOI
;
Yun Su CHOI
;
Ju yeon CHOI
;
Myung Guk HAN
;
Chun KANG
;
Jun Yong CHOI
Author Information
- Publication Type:Original Article
- Keywords: HIV infection; Hepatitis B virus; Hepatitis C virus; Coinfection
- MeSH: Antiretroviral Therapy, Highly Active; Cause of Death; Cohort Studies*; Coinfection*; Cross-Sectional Studies; Hepacivirus; Hepatitis B virus; Hepatitis B, Chronic; Hepatitis Viruses*; Hepatitis*; HIV Infections; HIV*; Humans*; Korea*; Liver Diseases; Logistic Models; Mortality; Prevalence; Risk Factors
- From:Infection and Chemotherapy 2017;49(4):268-274
- CountryRepublic of Korea
- Language:English
- Abstract: BACKGROUND: Despite declines in mortality and morbidity rates of patients with human immunodeficiency virus (HIV) infection as the result of highly active antiretroviral therapy, liver diseases due to chronic hepatitis B virus (HBV) and hepatitis C virus (HCV) infections are a leading cause of death among HIV-infected patients. However, HIV and HBV or HCV coinfection is still poorly documented, and more information is needed to better understand the characteristics of HIV-infected patients in Korea. MATERIALS AND METHODS: A cross-sectional study was performed to investigate clinical characteristics and prevalence of HBV and HCV infection in HIV patients enrolled in the Korea HIV/acquired immune deficiency syndrome (AIDS) cohort study from 17 institutions between December 2006 and July 2013. RESULTS: Among the 1,218 HIV-infected participants, 541 were included in this study. The prevalence of HBV-HIV and HCV-HIV coinfection was 5.0% (27/541) and 1.7% (9/541), respectively. There was no patient who was positive for both HBs antigen and HCV antibody. In multivariate logistic regression analysis, HBV unvaccinated status was a significant risk factor for HBV-HIV coinfection (odds ratio = 4.95, 95% confidence interval = 1.43–17.13). CONCLUSIONS: HBV and HCV infection was more common in HIV-infected persons enrolled in the Korean HIV/AIDS cohort, than in the general population in Korea.
