Research Progress in TCM for the Improvement of Nasal Mucosa Remodeling after Endoscopy in Chronic Sinusitis
10.19879/j.cnki.1005-5304.202211781
- VernacularTitle:中医药改善慢性鼻窦炎内镜术后鼻黏膜重塑研究进展
- Author:
Jiling LIU
1
;
Ling ZHOU
;
Xutao YAO
;
Yan WU
Author Information
1. 黑龙江中医药大学,黑龙江 哈尔滨 150040
- Keywords:
sinusitis;
nasal mucosa remodeling;
inflammation;
immunity;
mucosal epithelialization;
TCM;
review
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2024;31(1):185-190
- CountryChina
- Language:Chinese
-
Abstract:
TCM for the improvement of nasal mucosa remodeling after chronic sinusitis endoscopy is the key to the effective prevention of new lesions and recurrence in the surgical cavity mucosa.This article reviewed the mechanism of the nasal mucosa remodeling phenomenon after chronic sinusitis endoscopy and the unique advantages of TCM treatment.Deficiency,phlegm and blood stasis leading to"lung loss"is the perennial root of nasal mucosa remodeling.The treatment is"tonifying deficiency and removing phlegm,invigorating qi and promoting blood circulation",using acupuncture and medicine,and both internal and external treatment to regulate Th17/Treg balance and reduce the inflammatory infiltration;blocking the phosphorylation of MAPK and NF-κB pathway to inhibit TGF-β1-induced myofibroblasts,reduce collagen deposition and inhibit their remodeling,and promote the process of mucosal epithelialization,which can provide ideas for the theoretical and clinical treatment of TCM prevention and treatment of nasal mucosa remodeling.
