Research progress on the relationship between neurogenic bowel dysfunction and intestinal flora in cervical spinal cord injury
10.3969/j.issn.1008-9691.2023.06.024
- VernacularTitle:颈脊髓损伤神经源性肠道功能障碍与肠道菌群的关系研究进展
- Author:
Guifang WANG
1
;
Gaiqi YAO
Author Information
1. 北京大学第三医院危重医学科,北京 100191
- Keywords:
Intestinal flora;
Cervical spinal cord injury;
Neurogenic bowel dysfunctions;
Brain-gut axis
- From:
Chinese Journal of Integrated Traditional and Western Medicine in Intensive and Critical Care
2023;30(6):755-759
- CountryChina
- Language:Chinese
-
Abstract:
Cervical spinal cord injury can not only cause serious physical movement and sensory disorders but also lead to serious complications affecting the life safety and quality of life of patients.As the largest microecosystem in the human body,intestinal flora plays a very important role in maintaining host homeostasis and the occurrence and development of many diseases.In recent years,there has been increasing focus on the study of intestinal flora after spinal cord injury,leading to a growing recognition of the clinical value of intestinal flora in the treatment of spinal cord injury.Intestinal flora is not only related to the degree of spinal cord injury but also can provide therapeutic targets for neurogenic intestinal dysfunction after spinal cord injury.This paper discusses the mechanism of intestinal flora in the vagus nerve,hypothalamic-pituitary-adrenal axis,and metabolites after spinal cord injury.It explores the relationship between the occurrence and development of neurogenic intestinal dysfunction and changes in intestinal flora,offering valuable insights for the diagnosis and treatment of related diseases.
