Predictive Value of Ultrasound Radiomics Nomogram of Lymph Node Metastasis in Papillary Thyroid Carcinoma
10.3969/j.issn.1005-5185.2024.01.004
- VernacularTitle:超声影像组学诺模图预测甲状腺乳头状癌淋巴结转移的价值
- Author:
Qianqian YAN
1
;
Yufang ZHAO
;
Liping LIU
;
Wu CHEN
;
Guoqiang YANG
Author Information
1. 山西医科大学第一医院影像科,山西 太原 030001;山西省肿瘤医院,中国医学科学院肿瘤医院山西医院,山西医科大学附属肿瘤医院超声科,山西 太原 030013
- Keywords:
Thyroid cancer,papillary;
Lymph node metastasis;
Ultrasonography;
Radiomics;
Nomogram
- From:
Chinese Journal of Medical Imaging
2024;32(1):21-27
- CountryChina
- Language:Chinese
-
Abstract:
Purpose To investigate the value of ultrasound radiomics nomogram in predicting lymph node metastasis(LNM)of papillary thyroid carcinoma(PTC).Materials and Methods A retrospective analysis was conducted on 400 cases of PTC in the First Hospital of Shanxi Medical University from March 2021 to January 2022 confirmed by surgery and pathology,all of which underwent preoperative ultrasound examination,and were randomly divided into training cohort(n=280)and testing cohort(n=120)in a ratio of 7∶3.The relationship between ultrasound clinical features and LNM was evaluated via univariate analysis and a clinical model was established via multivariable Logistic regression.A total of 3 348 features were extracted from preoperative ultrasound images.Pearson correlation coefficient was used to screen the features,and Logistic regression was used to establish the radiomics model.Clinical risk factors and rad scores were combined to construct the nomogram,and the receiver operating characteristic curves and decision curve analysis were applied to evaluate the predictive efficacy and clinical benefit of each model for LNM of PTC.Results Age,primary lesion size,C-TIRADS and ultrasound-reported LNM were the independent risk factors for LNM(t/χ2=2.938,55.923,30.081,34.639,all P<0.05).The area under the curve of ultrasound radiomics nomogram to predict LNM of PTC in the training cohort and the testing cohort was 0.860 and 0.847,respectively;the combined model in 43%-85%had the highest clinical benefit.Conclusion Ultrasound radiomics nomogram has a certain value in predicting LNM of PTC.
