Predicting the formation of aortic dissection using a non-Newtonian model
10.3969/j.issn.1005-202X.2023.12.018
- VernacularTitle:基于非牛顿血液模型预测主动脉夹层的形成
- Author:
Miao WANG
1
;
Ji YAO
;
Yi SUN
;
Huimin WANG
;
Hongming ZHANG
Author Information
1. 昆明理工大学建筑工程学院,云南昆明 650500
- Keywords:
aortic dissection;
bidirectional fluid-solid coupling;
non-Newtonian blood;
hemodynamics;
hypertension
- From:
Chinese Journal of Medical Physics
2023;40(12):1571-1576
- CountryChina
- Language:Chinese
-
Abstract:
The blood flow in the aortic arch and branch vessels in vitro is simulated,and the blood model is optimized with a non-Newtonian model.A numerical simulation analysis is conducted based on bidirectional fluid-solid coupling to analyze the hemodynamic characteristics(blood flow velocity,vascular wall pressure and vascular wall stress)in a cardiac cycle,and discuss their relationships with the formation of aortic dissection.It is concluded that the long-term existence of"chaotic"blood flow distribution in the blood vessel and the sudden changes of wall pressure and wall stress are liable to cause changes in the structure and function of the cells of the arterial wall,and ultimately induce the formation of aortic dissection.The study provides a more reliable basis for medical diagnosis,and further protects the life,health and safety of patients.
