Research progress into the mechanisms of exosome immunoregulation of bacterial infection
10.3969/j.issn.1671-7856.2024.01.021
- VernacularTitle:外泌体对细菌感染免疫调节机制的研究进展
- Author:
Shuling LI
1
;
Zhiwei LI
Author Information
1. 新疆医科大学,乌鲁木齐 830000
- Keywords:
bacteria;
exosomes;
miRNA;
lncRNA;
protein;
immunoregulation
- From:
Chinese Journal of Comparative Medicine
2024;34(1):158-164
- CountryChina
- Language:Chinese
-
Abstract:
Exosomes are small endosomally derived extracellular vesicles with a lipid bilayer structure,and they contain substances,such as proteins,lipids,DNA,RNA,micro(mi)RNA,and long non-coding(lnc)RNA.Exosomes participate in pathogen recognition,antigen presentation,autophagy regulation,immune activation and immunosuppression in bacterial infections.Studies have shown that miRNA,lncRNA,and proteins in exosomes play important roles in regulating antibacterial reactions in organisms.We reviewed the immunomodulatory effects of exosomes on several intracellular and extracellular bacterial infections to provide a reference for those studying the interactions between exosomes and bacterial infections.
