Research progress on the application of a zebrafish model in breast cancer research
10.3969/j.issn.1005-4847.2023.12.014
- VernacularTitle:模式动物斑马鱼在人乳腺癌疾病研究中的应用进展
- Author:
Min ZHANG
1
;
Jingjing ZHANG
;
Guozhu NING
Author Information
1. 广东医科大学附属医院湛江市斑马鱼发育与疾病动物模型重点实验室,广东 湛江 524001
- Keywords:
zebrafish;
xenotransplantation mode;
breast cancer
- From:
Acta Laboratorium Animalis Scientia Sinica
2023;31(12):1629-1635
- CountryChina
- Language:Chinese
-
Abstract:
The zebrafish xenograft model plays an important role in cancer modelling,especially breast cancer xenografts.This model facilitates the real-time observation of tumor cell growth,metastasis,and interactions with the immune system,thus providing novel insights and experimental foundations for breast cancer treatment.Furthermore,the zebrafish xenograft model offers a valuable tool for high-throughput drug screening.This review provides an overview of the contributions of the zebrafish xenograft model to elucidating the mechanisms underlying breast cancer development,and its use in screening anti-tumor drugs and conducting therapeutic research.
