Epidemiological investigation of the first psittacosis death case in Hangzhou City,China
10.3969/j.issn.1002-2694.2024.00.010
- VernacularTitle:杭州市首例鹦鹉热死亡病例流行病学调查研究
- Author:
Zhe WANG
1
;
Zhou SUN
;
Shuang FENG
;
Ming-Yong TAO
;
Xin-Ye JIN
;
Yi WANG
;
Liu-Wen YANG
Author Information
1. 杭州市疾病预防控制中心传染病防制所,杭州 310021
- Keywords:
Chlamydia psittaci;
death cases;
epidemiologic investigation;
metagenomics next-generation sequencing
- From:
Chinese Journal of Zoonoses
2024;40(1):90-94
- CountryChina
- Language:Chinese
-
Abstract:
This study was aimed at performing epidemiologic investigation of the first psittacosis death case in Hangzhou City,to provide a reference for the investigation and disposal of psittacosis cases,as well as prevention and control.Epidemio-logic data were collected through field epidemiologic investigation,and close contacts and environmental samples were collected for pathogenicity testing.The first symptom in the patient was cough,which did not raise concerns at the time.Several days later,the patient developed abdominal distension and black stools,and visited two medical institutions for treatment and hospi-talization.The patient's sputum and peripheral blood were tested for Chlamydia psittaci infection by metagenomic analysis via next-generation sequencing.Samples collected from the patient's family members,close contacts,and home environment test-ed negative with real-time quantitative polymerase chain reaction.The patient later died of gastrointestinal bleeding.This article is the first report of a case of psittacosis contracted from exposure to a sick parrot in Hangzhou City,in a patient who died be-cause of an underlying disease.Operational training should be provided for medical personnel,and early diagnosis with mNGS and treatment of patients with underlying diseases should be performed as early as possible to avoid fatality.In addition,health education should be carried out to raise public awareness of the disease.
