The interaction between the coronavirus and the host from a metabolic point of view
10.3969/j.issn.1002-2694.2023.00.126
- VernacularTitle:从代谢角度看冠状病毒与宿主的相互作用
- Author:
Zi-Xin HUANG
1
;
Shu-Ting ZHOU
;
Zhe WANG
Author Information
1. 上海交通大学农业与生物学院动物科学系/上海市现代种业协同创新中心,上海 200240;上海市兽医生物技术重点实验室,上海 200240
- Keywords:
coronavirus;
cellular metabolism;
drug targets
- From:
Chinese Journal of Zoonoses
2023;39(11):1072-1079
- CountryChina
- Language:Chinese
-
Abstract:
The emergence of severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)triggered the global pandemic of novel coronavirus pneumonia and brought the"coronavirus"into the public eye.It is well known that rapid replication of vi-ruses can cause drastic metabolism changes in host cell,and recent studies have found corresponding antiviral targets from these key changes.In this review,we focus on recent studies on the effects of coronavirus on host metabolism,including lipid metabolism,central carbon metabolism,amino acid metabolism etc.Identifying host cell metabolic induced viral infection not only helps to better understand virus-host interactions,but also helps to develop potential antiviral strategies by targeting meta-bolic alterations.
