Research progress on role of cytokines in pathogenesis of connective tissue disease-associated interstitial lung disease
10.3969/j.issn.1000-484X.2024.03.036
- VernacularTitle:细胞因子在结缔组织病相关间质性肺病发病机制中的作用研究进展
- Author:
Yiping LIU
1
;
Fei YAN
;
Rong ZHANG
Author Information
1. 中国医科大学附属第一医院,沈阳 110001
- Keywords:
Connective tissue disease;
Interstitial lung disease;
Cytokines
- From:
Chinese Journal of Immunology
2024;40(3):651-655,662
- CountryChina
- Language:Chinese
-
Abstract:
Interstitial lung disease(ILD)is one of common pulmonary complications of connective tissue disease(CTD),which seriously affects quality of life and significantly increases risk of death of patients with CTD.However,related immune mecha-nism of CTD-ILD is not clear yet.This paper systematically reviews involvement of various cytokines in pathogenesis of CTD-ILD.Pathogenesis of CTD-ILD and correlation between cytokines and clinical indicators were discussed from cell level,animal model and clinical trials,to investigate whether cytokines can be targeted for treatment of CTD-ILD to help guide future research and clinical practice.
