Research progress on regulation of glucocorticoids on immune cells
10.3969/j.issn.1000-484X.2024.01.004
- VernacularTitle:糖皮质激素对免疫细胞调控的研究进展
- Author:
Jiarong LI
1
;
Jiyan ZHANG
Author Information
1. 南华大学药学院,南华大学药物药理研究所,衡阳 421001
- Keywords:
Stress;
Immunity;
Glucocorticoids
- From:
Chinese Journal of Immunology
2024;40(1):31-36
- CountryChina
- Language:Chinese
-
Abstract:
The immune system is the defender of human health,whose dysregulation is the source of various diseases.Re-duced immune defense and immune surveillance capabilities lead to difficulties in removing pathogens and malignant cells,thus increasing morbidity and mortality risk.Stress is a major factor in the decline of the immune system.In past studies,it has been demon-strated both in animal and humans that stress increases the levels of neuroendocrine hormones in the body,particularly glucocorticoids and catecholamines.Through the action of these stress hormones,stress has a number of detrimental effects on immune function,and this review combs through the progress of research on the regulation of immune cells by glucocorticoids.
