Meta-analysis on failure mode and effect analysis for the prevention of ICU-acquired infection
	    		
		   		
		   			
		   		
	    	
    	 
    	10.12138/j.issn.1671-9638.20244371
   		
        
        	
        		- VernacularTitle:失效模式与效应分析预防ICU获得性感染的Meta分析
 
        	
        	
        	
        		- Author:
	        		
		        		
		        		
			        		Ling-Ling GUO
			        		
			        		
			        		
			        			1
			        			
			        		
			        		
			        		
			        		
			        		;
		        		
		        		
		        		
			        		Xiao-Ying WU
			        		
			        		
		        		
		        		
		        		
		        		
		        			
			        		
			        		Author Information
			        		
		        		
		        		
			        		
			        		
			        			1. 重庆医科大学附属永川医院医院感染控制科,重庆 402160
			        		
		        		
	        		
        		 
        	
        	
        	
        	
        		- Keywords:
        			
	        			
	        				
	        				
			        		
				        		failure mode and effect analysis;
			        		
			        		
			        		
				        		ICU-acquired infection;
			        		
			        		
			        		
				        		multidrug-resistant organism infection;
			        		
			        		
			        		
				        		Me-ta-analysis;
			        		
			        		
			        		
				        		healthcare-associated infection
			        		
			        		
	        			
        			
        		
 
        	
            
            
            	- From:
	            		
	            			Chinese Journal of Infection Control
	            		
	            		 2024;23(3):336-343
	            	
            	
 
            
            
            	- CountryChina
 
            
            
            	- Language:Chinese
 
            
            
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		        	Abstract:
			       	
			       		
				        
				        	Objective To systematically evaluate the effectiveness of failure mode and effect analysis(FMEA)in the prevention of intensive care unit(ICU)-acquired infection.Methods Two researchers independently searched relevant literatures from foreign and Chinese databases,with a search deadline of July 15,2022.Independent screening of literatures,extraction of data and evaluation on overall quality were performed according to inclusion and exclusion criteria.RevMan 5.4 software was used to conduct Meta-analysis on the preventive effect of the in-cluded literatures.Results A total of 19 literatures were included in analysis.Meta-analysis results showed that ap-plication of FMEA method reduced the incidences of ventilator-associated pneumonia(OR=0.40,95%CI[0.31-0.51],P<0.01),catheter-associated urinary tract infection(OR=0.29,95%CI[0.17-0.51],P<0.01),cen-tral line-associated bloodstream infection(OR=0.28,95%CI[0.18-0.46],P<0.01),and multidrug-resistant organism infection(OR=0.46,95%CI[0.37-0.58],P<0.01)in ICU patients,as well as incidence of health-care-associated infection(HAI)in ICU(OR=0.46,95%CI[0.37-0.59],P<0.01),and significantly improved the satisfaction of ICU patients and their families(OR=2.34,95%CI[1.72-3.17],P<0.01).Conclusion FMEA can effectively prevent ICU-acquired infection and improve the quality of HAI management.