Three-dimensional Fluid-Structure Interaction Model of Venous Valve Based on Immersed Boundary/Finite Element Method
10.16156/j.1004-7220.2024.01.006
- VernacularTitle:建立基于浸入边界有限元法的三维静脉瓣流固耦合数值模型
- Author:
Bo WANG
1
;
Yang HAN
;
Nan QI
Author Information
1. 山东大学 数学与交叉科学研究中心;教育部非线性期望前沿科学中心;海洋研究院,山东 青岛 266237
- Keywords:
fluid-structure interaction(FSI);
venous valve;
immersed boundary method;
finite element analysis;
three-dimensional(3D)model
- From:
Journal of Medical Biomechanics
2024;39(1):40-45
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the dynamic process of fluid-structure interaction(FSI)between venous blood and valves and the physiological mechanism that guarantees unidirectional blood reflux back to the heart.Methods A three-dimensional(3D)numerical model of the venous system was established using the immersed boundary/finite element method.In the simulation,information from medical images of human lower-extremity veins and the anatomical structure and size of the bovine great saphenous vein were applied.Moreover,a hyperelastic constitutive model was used to describe the incompressible,nonlinear,and hyperelastic mechanical responses of the venous valve under physiological conditions.Results The simulations visualized the process of venous blood transport and the function of venous valves in preventing reflux.The periodic characteristics of venous valve motion and blood flow were reproduced,and important physiological data during the entire cardiac cycle were discussed and quantified,including the pressure,velocity,and flow rate of venous blood;opening area of the venous valve;and stress and strain distributions on the valve surface.Conclusions The 3D FSI model numerically reproduces the physiological dynamic process within veins and potentially provides important references and guidance for revealing the pathological mechanism of venous diseases.
