Role of neutrophil extracellular traps in viral myocarditis
10.3969/j.issn.1008-0074.2024.01.25
- VernacularTitle:中性粒细胞胞外诱捕网在病毒性心肌炎中的作用
- Author:
Wei SONG
1
;
Shuang YANG
Author Information
1. 哈尔滨医科大学附属第二医院心内科,黑龙江 哈尔滨 150081
- Keywords:
Myocarditis;
Viruses;
Neutrophils
- From:
Chinese Journal of cardiovascular Rehabilitation Medicine
2024;33(1):110-113
- CountryChina
- Language:Chinese
-
Abstract:
Viral myocarditis(VMC)is a common clinical cardiovascular disease,and inflammatory immune response is the main cause of VMC.Role that neutrophils play in VMC as a part of innate immune response has rarely been studied in the past.However,several studies have indicated that neutrophils can be involved in a variety of diseases through formation of a new defense mechanism called neutrophil extracellular traps(NETs).Moreover,NETs formation has been recently dis-covered in patients with active myocarditis and in myocardial pathological biopsies of VMC model,thus NETs are presumed to play a certain role in pathogenesis of VMC.The present article makes a review on role of NETs in VMC.
