Research progress on role of capsaicin in prevention and treatment of cardiovascular diseases
10.3969/j.issn.1008-0074.2023.06.23
- VernacularTitle:辣椒素对心血管疾病防治作用的研究进展
- Author:
Hong-Yuan JU
1
;
Ke-Rou LI
;
Ying-Wei DONG
Author Information
1. 哈尔滨医科大学附属第一医院 麻醉科,黑龙江 哈尔滨 150001
- Keywords:
Cardiovascular disease;
Vanillic acid;
Neuropeptides
- From:
Chinese Journal of cardiovascular Rehabilitation Medicine
2023;32(6):645-649
- CountryChina
- Language:Chinese
-
Abstract:
Capsaicin(CAP)is an extract of capsicum,a member of vanillin compounds,which possesses important value in prevention and treatment of cardiovascular diseases.Transient receptor potential vanilloid(TRPV)1 is a specific receptor of CAP,widely expressed in nervous system,cardiovascular system etc.In recent years,a large number of studies have indicated that CAP protects cardiovascular system by activating TRPV1,releasing a variety of neuropeptides through multiple signaling pathways.The present article makes a review on pharmacological action of CAP and its role in prevention and treatment of cardiovascular diseases,aiming at providing new thinking for pre-vention and treatment of cardiovascular diseases.
