Diagnostic value of LP(a),D-D combined LAD for LATH in atrial fibrillation
10.3969/j.issn.1008-0074.2023.06.11
- VernacularTitle:Lp(a)、D-D联合LAD对房颤并发LATH的诊断价值
- Author:
Hong-Bin PAN
1
;
Xiu-Feng LUO
;
Lian ZENG
;
Meng-Ju SHI
Author Information
1. 广西壮族自治区南溪山医院心血管内科,广西 桂林 541004
- Keywords:
Atrial fibrillation;
Thrombosis;
Lipoprotein(a)
- From:
Chinese Journal of cardiovascular Rehabilitation Medicine
2023;32(6):600-603
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To study diagnostic value of left atrial diameter(LAD),lipoprotein(a)[LP(a)]combined D-dimer(D-D)for left atrial thrombus(LATH)in patients with atrial fibrillation(AF).Methods:According to results of transesophageal echocardiography,a total of 367 AF patients treated in our hospital were divided into LATH group(n=67)and no LATH group(n=300).General clinical data,LAD,serum Lp(a)level and positive D-D rate were compared between two groups,and diagnostic value of above indexes for LATH in AF was ana-lyzed.Results:Compared with no LATH group,there were significant rise in LAD[(40.93±4.69)mm vs.(44.65±4.31)mm],serum Lp(a)level[(17.05±2.31)mg/dl vs.(27.42±3.06)mg/dl]and positive D-D rate(5.67%vs.22.34%)in LATH group(P=0.001 all).ROC curve indicated that AUC of Lp(a),positive D-D,LAD single detection and triple combined detection diagnosing LATH in AF was 0.711,0.584,0.728 and 0.801 respectively;sensitivity was 43.28%,22.39%,64.18%and 65.67%respectively;and specificity was 92.00%,94.33%,76.67%and 80.67%respectively.AUC of triple combined detection was significantly higher than that of any single detection,and sensitivity and specificity were significantly higher than those of Lp(a)and positive D-D single detection(P＜0.05 or＜0.01).Conclusion:Combined detection of Lp(a),positive D-D and LAD possess high diagnostic value for left atrial thrombus in atrial fibrillation.
