Progress on surveillance of Carbapenem-resistant Enterobacteriaceae colonization in children
10.3760/cma.j.issn.1673-4912.2024.02.009
- VernacularTitle:儿童患者碳青霉烯耐药肠杆菌定植筛查的相关研究进展
- Author:
Ling LIU
1
;
Gangfeng YAN
;
Guoping LU
Author Information
1. 复旦大学附属儿科医院重症医学科，上海 201102
- Keywords:
Carbapenem resistance;
Enterobacteriaceae;
Nosocomial infection;
Surveillance;
Children
- From:
Chinese Pediatric Emergency Medicine
2024;31(2):126-130
- CountryChina
- Language:Chinese
-
Abstract:
Carbapenem-resistant Enterobacteriaceae（CRE）is one of the common pathogens of hospital-acquired infections and has been widely spread in various countries，becoming one of the important public health problems worldwide.With the increase in the proportion of pediatric patients with CRE infections，studies related to the prevention and the control of CRE nosocomial infections have focused more on this group in recent years.Early prevention is particularly important because of the very limited treatment options for CRE infections and the high morbidity and mortality rates.Active screening，as a core measure to prevent CRE infection，has been implemented in several countries in recent years and has been shown to have a positive effect on the prevention and control of nosocomial infection in CRE.The target population of active screening generally includes people in close contact with CRE patients and people at high risk of CRE infection；screening specimens are mostly used in perianal swabs or rectal swabs；detection methods include bacterial culture and molecular detection techniques，with the former being the main method；the timing of screening is to collect the initial specimen within 24 hours of new admission，and follow up people at high risk of infection with regular testing.
