Progress of Research on Medical Application of Hydrogen in Digestive System
	    		
		   		
		   			
		   		
	    	
    	 
    	10.3969/j.issn.1008-7125.2023.09.010
   		
        
        	
        		- VernacularTitle:氢气在消化系统中医学应用的研究进展
 
        	
        	
        	
        		- Author:
	        		
		        		
		        		
			        		Peng CHEN
			        		
			        		
			        		
			        			1
			        			
			        		
			        		
			        		
			        		
			        		;
		        		
		        		
		        		
			        		Tao HU
			        		
			        		;
		        		
		        		
		        		
			        		Zhiwei HAN
			        		
			        		;
		        		
		        		
		        		
			        		Ling XU
			        		
			        		
		        		
		        		
		        		
		        		
		        			
			        		
			        		Author Information
			        		
		        		
		        		
			        		
			        		
			        			1. 传染病疫苗研发全国重点实验室 翔安创新实验室 分子疫苗学和分子诊断学国家重点实验室疫苗研究产教融合国家创新平台 厦门大学公共卫生学院(361102)
			        		
		        		
	        		
        		 
        	
        	
        	
        	
        		- Keywords:
        			
	        			
	        				
	        				
			        		
				        		Hydrogen;
			        		
			        		
			        		
				        		Digestive System Diseases;
			        		
			        		
			        		
				        		Mouth Disease;
			        		
			        		
			        		
				        		Anti-Oxidation;
			        		
			        		
			        		
				        		Anti-Inflammation
			        		
			        		
	        			
        			
        		
 
        	
            
            
            	- From:
	            		
	            			Chinese Journal of Gastroenterology
	            		
	            		 2023;28(9):566-571
	            	
            	
 
            
            
            	- CountryChina
 
            
            
            	- Language:Chinese
 
            
            
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		        	Abstract:
			       	
			       		
				        
				        	The medical application of hydrogen is one of the hotspots in recent years.Hydrogen has small molecular weight,strong diffusion ability and certain reducibility,which can react with reactive oxygen species in the body.At present,hydrogen has been proven to have good preventive and therapeutic effects in various diseases.In recent years,hydrogen-rich water and hydrogen-rich saline have been widely used as the main hydrogen intervention methods in fundamental and clinical research related to the digestive system.Several studies have proved that hydrogen-rich solution has a certain improvement effect on various diseases in the digestive system,such as oral diseases,intestinal barrier damage,inflammatory bowel disease,pancreatitis,liver disease,digestive system tumors,etc.The mechanism related to the biological effects of hydrogen includes anti-oxidation,anti-inflammation,anti-apoptosis,regulation of energy metabolism,modulation of gut microbiota and signal transduction.Therefore,this article aims to review the research progress on the medical effects and mechanisms of hydrogen in the digestive system.