Constitution-Based Toxicology:A New Perspective of Study for Assessing the Safety of Traditional Chinese Medicine
- VernacularTitle:体质毒理学:中药安全性评价的新方向
- Author:
Chuanxin LIU
1
;
Jiao KONG
Author Information
- Keywords: Constitution-based toxicology; Contraindication with Constitution differentiation; Constitution differentiation-disease differentiation-syndrome differentiation; Toxicological evidence chain; Safety evaluation of traditional Chinese medicine
- From: World Science and Technology-Modernization of Traditional Chinese Medicine 2023;25(12):3776-3784
- CountryChina
- Language:Chinese
- Abstract: At present,research on the safety of traditional Chinese medicine mainly follows the modern medical system,neglecting the crucial role of body factors in adverse events.This research first proposed a new way of thinking about"Constitution-based toxicology"research based on"Contraindication with Constitution differentiation",with"constitutional-herb mutual exclusion"as the core,guided by"Constitution differentiation-disease differentiation-syndrome differentiation"and"Properties Theory of Chinese Medicinal Herbs",with the"toxicological evidence chain"as the method,the pharmacovigilance theory as the foundation,and supported by advanced analytical technology.Constitution-based toxicology,a new interdisciplinary field combining TCM toxicology and TCM constitution theory,is a novel advancement of traditional Chinese medicine.It offers the groundwork for advancing the methodical design of traditional Chinese medicine safety evaluation.
