Study on the correlation between sympathetic nerve excitability and the occurrence and development of wake-up stroke
	    		
		   		
		   			
		   		
	    	
    	 
    	10.3969/j.issn.1004-1648.2024.02.001
   		
        
        	
        		- VernacularTitle:交感神经兴奋性与醒后脑卒中发生发展的相关性研究
 
        	
        	
        	
        		- Author:
	        		
		        		
		        		
			        		Jing WANG
			        		
			        		
			        		
			        			1
			        			
			        		
			        		
			        		
			        		
			        		;
		        		
		        		
		        		
			        		Junli LÜ
			        		
			        		;
		        		
		        		
		        		
			        		Hongliang LIAN
			        		
			        		
		        		
		        		
		        		
		        		
		        			
			        		
			        		Author Information
			        		
		        		
		        		
			        		
			        		
			        			1. 056001 邯郸市中心医院神经内科
			        		
		        		
	        		
        		 
        	
        	
        	
        	
        		- Keywords:
        			
	        			
	        				
	        				
			        		
				        		stroke after waking up;
			        		
			        		
			        		
				        		occurrence and development;
			        		
			        		
			        		
				        		sympathetic nerve;
			        		
			        		
			        		
				        		correlation;
			        		
			        		
			        		
				        		risk factors
			        		
			        		
	        			
        			
        		
 
        	
            
            
            	- From:
	            		
	            			Journal of Clinical Neurology
	            		
	            		 2024;37(2):81-85
	            	
            	
 
            
            
            	- CountryChina
 
            
            
            	- Language:Chinese
 
            
            
            	- 
		        	Abstract:
			       	
			       		
				        
				        	Objective To analyze the correlation between sympathetic nerve excitability and the occurrence and development of wake-up stroke.Methods A total of 100 patients with acute stroke admitted to our hospital from July 2020 to January 2022 were selected and divided into wake-up stroke group and non-wake-up stroke group according to whether wake-up stroke occurred.Logistic regression model was established to analyze the relationship between sympathetic excitation and the occurrence and development of wake-up stroke.Results Multivariate analysis showed that blood pressure variability,heart rate variability,blood glucose variability,electrolytes disturbance,25-hydroxyvitamin D3,urinary vanilla bitter almond acid,and catecholamine were risk factors for the occurrence and development of stroke after waking up(all P<0.05).Conclusions Sympathetic nerve excitability is related to the occurrence and development of stroke after waking up.Blood pressure variability,heart rate variability,blood glucose variability,electrolyte disturbance,25-hydroxyvitamin D3,urinary vanilla bitter almond acid and catecholamine are risk factors for the occurrence and development of stroke after waking up.