Risk factors of acute kidney injury after primary total knee arthroplasty in patients with ASA physi-cal status Ⅰ or Ⅱ
- VernacularTitle:ASA Ⅰ或Ⅱ级患者全膝关节置换术后急性肾损伤的危险因素
- Author:
Hui XU
1
;
Lulu MA
Author Information
- Keywords: Acute kidney injury; Primary total knee arthroplasty; Perioperative transfusion; American Society of Anesthesiologists physical status
- From: The Journal of Clinical Anesthesiology 2023;39(12):1293-1296
- CountryChina
- Language:Chinese
- Abstract: Objective To determine the incidence of acute kidney injury in patients undergoing primary total knee arthroplasty with ASA physical status Ⅰ or Ⅱ.Methods A total of 2 623 patients from January 2014 to December 2019,513 males and 2 110 females,aged ≥ 18 years,ASA physical status Ⅰor Ⅱ,who underwent primary total knee arthroplasty were included.Demographic characteristics and perio-perative data were collected.AKI was diagnosed according to the criteria from Kidney Disease Improving Global Outcomes(KDIGO)and the patients were divided into two groups:AKI group and non-AKI group.Independent risk factors of acute kidney injury were evaluated by binary logistic regression.Results Forty-one patients(1.9％)developed acute kidney injury postoperatively.Binary logistic regression showed perio-perative transfusion(OR=3.979,95％CI 2.243-7.056,P＜0.001),the duration of operation(OR=1.007,95％CI 1.001-1.013,P=0.031)and perioperative combined use of antibiotics(vancomycin+cefuroxime/clindamycin)(OR=4.053,95％CI 1.350-12.165,P=0.013)were independent predic-tive factors of acute kidney injury.Conclusion Perioperative transfusion,longer duration of operation,and combined use of antibiotics(vancomycin+cefuroxime/clindamycin)were risk factors for postoperative AKI in patients with ASA physical status Ⅰ or Ⅱ.
