Research progress in nanoparticle-mediated cryoablation therapy for tumors

VernacularTitle:纳米颗粒介导冷冻消融治疗肿瘤的研究进展
Author: Fuming WANG ¹ ; Jijin YANG
Author Information

1. 200433 上海海军军医大学附属长海医院介入科
Keywords: nanoparticle; cryoablation; tumor
From: Journal of Interventional Radiology 2024;33(2):197-201
CountryChina
Language:Chinese
Abstract: Cryoablation is a local ablation treatment based on the hypothermia effect,which has been widely used in the treatment of various solid tumors throughout the body.However,low freezing efficiency and insufficient accuracy are the problems in clinical cryoablation therapy which need to be solved urgently.With the continuous progress of nanoscience,various types of nanoparticles have been developed and applied in clinical practice.After being loaded into the target area,the nanoparticles can exert functions such as targeted drug delivery as well as image enhancement,which provides the possibility to break through the current clinical application bottleneck of cryoablation therapy.This paper aims to make a comprehensive review about several currently commonly-used nanoparticles for cryoablation therapy,focusing on their main functions and mechanisms,with the hope that the physicians concerned can get a further detailed understanding of the nanoparticles and lay a solid foundation for conducting in-depth researches and achieving clinical transformation.