Role of Danggui Buxue Decoction for the prevention and treatment of cardiovascular and pulmonary diseases
10.11817/j.issn.1672-7347.2023.230198
- VernacularTitle:当归补血汤防治心肺疾病的作用
- Author:
Lin JIANG
1
;
Liping CHEN
;
Wenbin LI
;
Rong WANG
Author Information
1. 中国人民解放军联勤保障部队第九四〇医院药剂科,兰州 730050;甘肃中医药大学药学院,兰州 730050;甘肃省高原药学行业技术中心,兰州 730050
- Keywords:
Danggui Buxue Decoction;
cardiovascular and pulmonary diseases;
active ingredients;
pharmacological effect;
clinical application
- From:
Journal of Central South University(Medical Sciences)
2023;48(10):1479-1493
- CountryChina
- Language:Chinese
-
Abstract:
Cardiovascular and pulmonary diseases have become the major disease endangering people's physical and mental health because of its high morbidity and mortality.Danggui Buxue Decoction,a noteworthy classical prescription,is composed of astragali radix and angelicae sinensis radix at a ratio of 5∶1.It is a prescription for tonifying both vital energy and blood and has the effect of dredging collaterals.Its main active components,such as polysaccharides,saponins,flavonoids and volatile oils,have good effects on antioxidation,inflammation regulation,immune regulation and promotion of blood circulation.Danggui Buxue Decoction can improve myocardial ischemia-reperfusion injury and heart failure,relieve the symptoms of diabetic cardiomyopathy,inhibit pulmonary fibrosis,protect lung injury and fight against lung cancer and other cardiopulmonary diseases.Preclinical studies have showed that this prescription can inhibit inflammation and oxidative stress,regulate autophagy and enhance immune function through multi-target pathways.Reviewing the main effective components,pharmacological action and mechanism,and clinical application of Danggui Buxue Decoction are helpful to provide comprehensive information for the clinical application of Danggui Buxue Decoction in prevention and treatment of cardiovascular and pulmonary diseases.
