Discussion on medication law of TCM oral prescriptions for postherpetic neuralgia based on data mining
10.3760/cma.j.cn115398-20220904-00054
- VernacularTitle:基于数据挖掘探讨中药内服方治疗带状疱疹后遗神经痛用药规律
- Author:
Zerun ZHANG
1
;
Jiguo YANG
;
Yuanxiang LIU
Author Information
1. 山东中医药大学第一临床医学院2022级硕士研究生，济南 250355
- Keywords:
Neuralgia, postherpetic;
Ancient and Modern Medical Record Cloud Platform;
TCM oral prescriptions;
Medication law;
Data mining
- From:
International Journal of Traditional Chinese Medicine
2023;45(11):1453-1457
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To analyze the medication law of TCM oral prescriptions in the treatment of postherpetic neuralgia (PHN).Methods:The effective cases and clinical studies about TCM oral prescriptions in the treatment of PHN were retrieved from CNKI, Wanfang Data, VIP, and CBM from January 1, 2002 to December 31, 2021. The medication frequency and drug properties were counted through the Ancient and Modern Medical Record Cloud Platform, and correlation analysis, cluster analysis and complex network analysis were performed.Results:A total of 233 articles were included, involving 243 prescriptions and 191 kinds of Chinese materia medica. There were 20 kinds of Chinese materia medica with frequency >40, most of which have the efficacy of promoting blood circulation to remove blood stasis. The Chinese materia with heat-clearing and detoxifying efficacy were also often used. The properties were mainly warm, mild, slight cold, and cold, tastes were mainly bitter, pungent and sweet, and meridians were mainly liver, spleen and heart meridians. The association rule analysis was used to obtain 15 commonly used TCM groups. The commonly used Chinese materia medica could be clustered into 4 categories. The core prescription obtained by complex network analysis was Angelicae Sinensis Radix, Glycyrrhizae Radix et Rhizoma, Corydalis Rhizoma, Bupleuri Radix, Carthami Flos, Paeoniae Radix Alba, Persicae Semen, Chuanxiong Rhizoma, and Rehmanniae Radix.Conclusion:TCM oral prescriptions for the treatment of PHN put promoting blood circulation to remove blood stasis and activating meridians to stop pain in priority, taking into account the clearing heat, regulating qi and blood.
