Differentiation therapies in human cancers
10.3760/cma.j.cn371439-20231013-00016
- VernacularTitle:肿瘤的分化治疗
- Author:
Hongyun YUE
1
;
Baihong ZHANG
Author Information
1. 中国人民解放军联勤保障部队第九四〇医院眼科，兰州 730050
- Keywords:
Neoplasms;
Cell differentiation;
Drug therapy
- From:
Journal of International Oncology
2024;51(2):109-113
- CountryChina
- Language:Chinese
-
Abstract:
Cancer phenotypic plasticity includes dedifferentiation, blocked differentiation and trans- differentiation, and differentiation therapy targeting tumor cell plasticity is becoming a new therapeutic model for human cancers. The application of inducing differentiation, initiating differentiation and regulating differentiation in tumor differentiation therapy will promote the directed differentiation of tumor cells into mature cells and the remodeling of phenotypes, thus to achieve the purpose of cancer treatment.
