Progress on the mechanism of alveolar macrophages in children with respiratory tract virus infection
10.3760/cma.j.issn.1673-4408.2024.03.002
- VernacularTitle:肺泡巨噬细胞在儿童呼吸道病毒感染中的作用机制研究进展
- Author:
Xiaoping YUAN
1
;
Gen LU
Author Information
1. 广州医科大学附属妇女儿童医疗中心呼吸科 510120
- Keywords:
Children;
Alveolar macrophage;
Respiratory viruses;
Pathogenesis
- From:
International Journal of Pediatrics
2024;51(3):148-152
- CountryChina
- Language:Chinese
-
Abstract:
Virus is one of the common causes of respiratory tract infection in children.Viral infection involves the action of multiple immune cells and inflammatory mediators，understanding the immune mechanism of virus-host interaction during respiratory infection may be helpful for etiological diagnosis of viral infections.As the main immune cells of the lungs，alveolar macrophages on the mucosal surface of the respiratory tract play an important role in maintaining pulmonary immune homeostasis（immune monitoring，initiation and regulation of inflammatory response，killing pathogens）due to their unique position.This article will briefly review the immune regulation mechanism of alveolar macrophages in the occurrence and development of respiratory tract viral infection in children，in order to provide reference for the prevention and treatment of viral infection.
