Effects of clearing blockage of meibomian gland ducts prior to cataract surgery on dry eye and gland function
	    		
		   		
		   			
		   		
	    	
    	 
    	10.16016/j.2097-0927.202305049
   		
        
        	
        		- VernacularTitle:睑板腺疏通对白内障患者术后干眼症状和睑板腺功能的影响
 
        	
        	
        	
        		- Author:
	        		
		        		
		        		
			        		Jiaxin CAI
			        		
			        		
			        		
			        			1
			        			
			        		
			        		
			        		
			        		
			        		;
		        		
		        		
		        		
			        		Meifang LIU
			        		
			        		;
		        		
		        		
		        		
			        		Jing XIE
			        		
			        		;
		        		
		        		
		        		
			        		Xi LIU
			        		
			        		
		        		
		        		
		        		
		        		
		        			
			        		
			        		Author Information
			        		
		        		
		        		
			        		
			        		
			        			1. 400038 重庆,陆军军医大学(第三军医大学)第一附属医院眼科
			        		
		        		
	        		
        		 
        	
        	
        	
        	
        		- Keywords:
        			
	        			
	        				
	        				
			        		
				        		meibomian gland dysfunction;
			        		
			        		
			        		
				        		dry eye;
			        		
			        		
			        		
				        		cataract surgery;
			        		
			        		
			        		
				        		meibomian gland massage
			        		
			        		
	        			
        			
        		
 
        	
            
            
            	- From:
	            		
	            			Journal of Army Medical University
	            		
	            		 2024;46(3):288-293
	            	
            	
 
            
            
            	- CountryChina
 
            
            
            	- Language:Chinese
 
            
            
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		        	Abstract:
			       	
			       		
				        
				        	Objective To investigate the effects of clearing meibomian gland ducts prior to cataract surgery on the gland dysfunction and dry eye induced by surgery.Methods A prospective,randomized controlled trial was conducted on 110 patients(110 eyes)undergoing elective cataract surgery for senile cataract in our department from June 1,to December 31,2021.The participants were randomly allocated into treatment(n=56)and control(n=54)groups.The patients from the treatment group were given eyelid compresses and cleaning to remove an obstructed meibum in 1 week prior to cataract surgery,while those from the control group received no such treatment.Ocular surface disease index(OSDI),indicators related to meibomian gland function,including tear film lipid layer thickness(LLT),meibomian glands yielding liquid secretion(MGYLS),meibomian glands yielding secretion score(MGYSS),and tear film break-up time(TBUT)before,and 1 and 3 months after surgery were employed to evaluate the efficacy of clearing meibomian gland ducts.Results The control group exhibited significantly decreased MGYLS(P<0.05),increased MGYSS(P<0.01),thinner LLT(P<0.01),shorter TBUT,worsened dry eye symptoms,and elevated OSDI score(P<0.05)in 1 month after surgery.Conversely,the treatment group showed significantly improved MGYLS(P<0.01),decreased MGYSS(P<0.01),thicker LLT,extended TBUT,and improved subjective outcomes reported on OSDI.Conclusion Our preoperative meibomian gland treatment prior to cataract surgery may be a safe and effective intervention for relieving dry eye and meibomian gland dysfunction induced by surgery.