Application of AI diagnostic system in the evaluation of CHD patients in high-altitude areas
	    		
		   		
		   			
		   		
	    	
    	 
    	10.3969/j.issn.1671-8348.2024.05.017
   		
        
        	
        		- VernacularTitle:冠状动脉AI诊断系统在高海拔地区CHD患者评估中的应用价值
 
        	
        	
        	
        		- Author:
	        		
		        		
		        		
			        		Xueyan WANG
			        		
			        		
			        		
			        			1
			        			
			        		
			        		
			        		
			        		
			        		;
		        		
		        		
		        		
			        		Haihua BAO
			        		
			        		;
		        		
		        		
		        		
			        		Shengbao WEN
			        		
			        		;
		        		
		        		
		        		
			        		Yuntai CAO
			        		
			        		;
		        		
		        		
		        		
			        		Weixia LI
			        		
			        		;
		        		
		        		
		        		
			        		Mei YAN
			        		
			        		
		        		
		        		
		        		
		        		
		        			
			        		
			        		Author Information
			        		
		        		
		        		
			        		
			        		
			        			1. 青海大学附属医院医学影像中心,西宁 810000
			        		
		        		
	        		
        		 
        	
        	
        	
        	
        		- Keywords:
        			
	        			
	        				
	        				
			        		
				        		artificial intelligence;
			        		
			        		
			        		
				        		high altitude;
			        		
			        		
			        		
				        		coronary artery;
			        		
			        		
			        		
				        		CT angiography;
			        		
			        		
			        		
				        		hemodynamics
			        		
			        		
	        			
        			
        		
 
        	
            
            
            	- From:
	            		
	            			Chongqing Medicine
	            		
	            		 2024;53(5):733-737
	            	
            	
 
            
            
            	- CountryChina
 
            
            
            	- Language:Chinese
 
            
            
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		        	Abstract:
			       	
			       		
				        
				        	Objective To explore the application of diagnostic system with artificial intelligence(AI)in the evaluation of patients with coronary heart disease(CHD)at high altitude.Methods A total of 318 pa-tients underwent coronary CT angiography(CTA)at the hospital from January to December 2022 were pro-spectively collected.According to the altitude gradient,the patients were divided into the 2 000-3 000 m group and>3 000 m group.Coronary angiography(CAG)was used as the gold standard to verify the diag-nostic performance of AI diagnostic system.Coronary artery diagnosis system with AI technology and CT de-rived fractional flow reserve(CT-FFR)measurement system were used to evaluate the plaque structure char-acteristics and hemodynamic changes in the two groups of patients.Results Calcified plaques and vulnerable plaques in the>3 000 m group were more than those in the 2 000-3 000 m group(χ2=3.976,6.482,P= 0.046,0.011).The incidence of multi-vessel coronary artery disease,moderate stenosis,severe stenosis and complete occlusion in the>3 000 m group was higher than that in the 2 000-3 000 m group,and the inci-dence of single-vessel coronary artery disease and mild stenosis in the 2 000-3 000 m group was higher than that in the>3 000 m group(P<0.05).The incidence of CT-FFR≤0.80 and<0.70 in the>3 000 m group was higher than that in the 2 000-3 000 m group(χ2=4.782,28.118,P=0.029,<0.001).The comparison with the gold standard showed that this method has high sensitivity,specificity,and diagnostic consistency(P<0.001).Conclusion The coronary diagnosis system with AI technology has certain value in the system-atic evaluation of coronary artery characteristics and hemodynamic changes in CHD patients at high altitude.