Current status and prospect of diagnosis and treatment of neonatal lactose intolerance
	    		
		   		
		   			
		   		
	    	
    	 
    	10.3969/j.issn.1671-8348.2024.05.001
   		
        
        	
        		- VernacularTitle:新生儿乳糖不耐受诊疗的现状与展望
 
        	
        	
        	
        		- Author:
	        		
		        		
		        		
			        		Zhengli WANG
			        		
			        		
			        		
			        			1
			        			
			        		
			        		
			        		
			        		
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			        		Yuan SHI
			        		
			        		
		        		
		        		
		        		
		        		
		        			
			        		
			        		Author Information
			        		
		        		
		        		
			        		
			        		
			        			1. 重庆医科大学附属儿童医院新生儿科/国家儿童健康与疾病临床医学研究中心/儿童发育疾病研究教育部重点实验室,重庆 400014;儿童感染与免疫罕见病重庆市重点实验室,重庆 400014;重庆医科在学附属儿童医院江西医院,南昌 330038
			        		
		        		
	        		
        		 
        	
        	
        	
        	
        		- Keywords:
        			
	        			
	        				
	        				
			        		
				        		newborn;
			        		
			        		
			        		
				        		lactose intolerance;
			        		
			        		
			        		
				        		lack of lactase;
			        		
			        		
			        		
				        		lactase
			        		
			        		
	        			
        			
        		
 
        	
            
            
            	- From:
	            		
	            			Chongqing Medicine
	            		
	            		 2024;53(5):641-643,650
	            	
            	
 
            
            
            	- CountryChina
 
            
            
            	- Language:Chinese
 
            
            
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		        	Abstract:
			       	
			       		
				        
				        	Lactose intolerance refers to the poor absorption of lactose caused by insufficient number or low activity of lactase,which leads to one or more gastrointestinal symptoms.Newborns are mainly develop-mental and secondary lactase deficiency,with various clinical symptoms,which are easy to be missed and mis-diagnosed.Neonatal lactose intolerance is often diagnosed by fecal reducing sugar and pH determination and urinary galactose determination,but there are still many hospitals that have not carried out related inspection projects.Although there is currently a lack of specific guidelines for neonatal lactose intolerance,but in the context of promoting breastfeeding,reducing the abuse of special milk powder,and rational use of efficient,high-quality lactase is particularly important.In addition,a series of problems involved in the diagnosis and treatment of neonatal lactose intolerance in China need to be further explored.How to find a balance point in the treatment of lactose intolerance will be a direction for future research.