Evaluation of gastric emptying after preoperative oral carbohydrate administration in obese women:a non-inferiority study
10.3969/j.issn.1671-8348.2024.04.021
- VernacularTitle:肥胖女性术前口服碳水化合物后胃排空评估的非劣效性研究
- Author:
Yuhong LI
1
;
Zhiqiang REN
;
Ning YIN
Author Information
1. 南京医科大学附属逸夫医院麻醉科,南京 221000
- Keywords:
gastric ultrasound;
obesity;
carbohydrates;
laparoscopy;
gynecological surgery
- From:
Chongqing Medicine
2024;53(4):587-591
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate whether the gastric juice volume(GV)of obese women who took carbohydrate 2 hours before operation was equal to or less than that of those who are not routine drinking.Methods Obese patients undergoing elective laparoscopic gynecological surgery under general anesthesia with BMI of 28-32 kg/m2 and ASA grade of Ⅰ-Ⅱ,aged 18-65 years old were selected.The patients were divid-ed into the carbohydrate group(CHO group)and the fasting group(Control group)by random number table method,with 51 cases in each group.The Control group was fasted from 11 pm before surgery,while the CHO group was given 300 mL of carbohydrate orally 2 hours before anesthesia.The main outcome measure was compared with a non-inferiority limit(△)of 17 mL and the mean difference in gastric juice volume between the two groups in the right lateral decubitus position(RLDP)examined by gastric ultrasound.The secondary outcome measures included CSA in right lateral position under gastric ultrasound,Perlas classification,GV/kg,gastric juice pH value,patient satisfaction and gastric emptying time.Results The mean difference of gas-tric juice volume was 7.18 mL(95％CI:-0.06 to 14.43),and the upper limit of 95％CI was lower than the preset non-inferiority limit(△=17.05 mL).There was no statistically significant difference in the mean(standard deviation)gastric juice volume between the control group and the CHO group[40(26,66)mL vs.58(34,65)mL;P=0.43].The gastric volume GV/kg was similar in the two groups(P=0.66),and there was no significant difference in the number distribution of Perlas grades between the two groups(P＞0.05).There was significant difference in patient satisfaction between the two groups(P＜0.05).Conclusion Ac-cording to the evaluation of gastric ultrasound,compared with fasting at midnight,300ml carbohydrate intake at 2 hours before surgery is not inferior to fasting at midnight in terms of gastric fluid volume in obese women as assessed by gastric ultrasound.
