Clinical observation of hydromorphone combined with ropivacaine for anterior serratus plane block to relieve acute pain after breast cancer surgery
10.3969/j.issn.1671-8348.2024.04.018
- VernacularTitle:氢吗啡酮联合罗哌卡因前锯肌平面阻滞减轻乳腺癌术后急性疼痛的临床观察
- Author:
Wei WANG
1
;
Wei ZHANG
;
Keyu HE
;
Wei LI
Author Information
1. 重庆大学附属涪陵医院麻醉科,重庆 408000
- Keywords:
serratus anterior plane block;
breast cancer;
hydromorphone;
postoperative pain
- From:
Chongqing Medicine
2024;53(4):571-575,581
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the efficacy of hydromorphone combined with ropivacaine for serra-tus anterior plane block(SAPB)in acute pain after breast cancer surgery.Methods A total of 58 patients un-dergoing breast cancer surgery were divided into the hydromorphone combined with ropivacaine block group(group HR)and the Ropivacaine block group(group R)by the random number table method.Before surgery,the patients in the two groups were treated with SAPB.The patients in both groups underwent SAPB before surgery,and the dosage of opioids during surgery,the scores of Numeric Rating Scale(NRS)at 30 min,2 h,4 h,6 h,12 h,24 h and 48 h after surgery,the perioperative indicators related to block and the incidence of chro-nic pain after surgery were recorded.Results Compared with group R,the resting NRS score at 30 min,2 h,12 h,24 h and 48 h after surgery and exercise NRS score at 12 h,24 h and 48 h after surgery in group HR were decreased(P＜0.05),and after 12(0 vs.31.0％,P=0.020),24(27.6％vs.65.5％,P=0.040)and 48 h(6.9％vs.37.9％,P=0.005),the incidence of moderate and severe pain during exercise decreased.The pa-tients in group HR got out of bed earlier than those in group R[20(18,23)h vs.24(20,27)h,P=0.021].Conclusion Hydromorphone combined with ropivacaine SAPB can reduce the NRS score after breast cancer surgery,reduced the incidence of moderate to severe pain,and shorten the time for patients to get out of bed.
