The "four-dimensional theory" of metal element stress response
10.3969/j.issn.1671-8348.2024.02.001
- VernacularTitle:金属元素应激的"四维理论"
- Author:
Zhen ZOU
1
;
Chengzhi CHEN
Author Information
1. 重庆医科大学:生命科学研究院呼吸系统疾病分子生物学实验室,重庆 400016;重庆医科大学:公共卫生学院劳动卫生与环境卫生学教研室,重庆 400016
- Keywords:
metal element stress response;
four-dimensional theory;
biological effects;
physiological and pathological process
- From:
Chongqing Medicine
2024;53(2):161-164,170
- CountryChina
- Language:Chinese
-
Abstract:
Metal elements are the most common and widely distributed chemical elements in nature,which are closely related to human health,and their excess or lack will have a profound impact on the physio-logical and pathological processes of the body.This paper defines the concept of"metal element stress re-sponse",that is,the stress response that can occur in various cells,tissues and organs throughout the body when the content of metal elements in the body exceeds or falls below a certain level.According to the degree of stress,it can be divided into four dimensions:physiological stress,burden stress,pathological stress and disease stress.This paper comprehensively describes the degree,mode and biological effect of the interaction between metal elements and organism,and"four-dimensional theory"of metal element stress response is pro-posed,aiming to provide new ideas and new methods for seeking the potential intervention strategies of metal element stress response in the future
