Serum thyroid function, hs-CRP expression, and coagulation function in syphilis patients
10.3969/j.issn.1006-2483.2024.02.033
- VernacularTitle:梅毒患者血清甲状腺功能和hs-CRP表达水平及其凝血功能分析
- Author:
Xuan HU
1
;
Qian LI
2
;
Hao HE
3
Author Information
1. Department of Laboratory Medicine , Bazhong Central Hospital , Bazhong , Sichuan 636001 , China
2. Department of Radiology , Bazhong Central Hospital , Bazhong , Sichuan 636001 , China
3. Department of Infection , Bazhong Central Hospital , Bazhong , Sichuan 636001 , China
- Publication Type:Journal Article
- Keywords:
SyphilisSerum;
Serum;
Thyroid function;
Coagulation function
- From:
Journal of Public Health and Preventive Medicine
2024;35(2):144-147
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the serum levels of thyroid function and hs-CRP expression in patients with syphilis and their relationship with coagulation function. Methods A total of 80 syphilis patients admitted to Bazhong Central Hospital from January 2020 to January 2022 were selected as the study subjects and set as the observation group. In addition, 80 healthy individuals were selected as the control group, and 80 psoriasis patients were selected as the disease control group. Thyroid function, hs-CRP and coagulation function among different groups were compared. The correlation between thyroid function, hs-CRP, and coagulation function in patients with syphilis was analyzed, and the effectiveness of these parameters in predicting syphilis was analyzed. Results The values of FT3, FT4, TSH and hs-CRP in the observation group were higher than those in the control group and the disease control group (P<0.05). The abnormal rates of thyroid function and hs-CRP level in the observation group were higher than those in the control group and the disease control group (P<0.05). PT, APTT, and TT of the observation group were higher than those of the control group and the disease control group (P<0.05). The abnormal rate of coagulation function in the observation group was higher than that in the control group and the disease control group (P<0.05). The levels of FT3, FT4, TSH, hs-CRP, PT, APTT, and TT in the first stage were lower than those in the second and third stages, while these parameters in the secondary stage were lower than those in the third stage (P<0.05). The severity of syphilis was positively correlated with FT3, FT4, hs-CRP, APTT, and TT (P<0.05). Among these indicators, TT was more effective in the diagnosis of syphilis. Conclusion Syphilis patients have hyperthyroidism, accompanied by coagulation dysfunction and abnormal increase in hs-CRP, which are all related to the condition of syphilis patients. The combined prediction of syphilis patients has high effectiveness.
