Hp infection rate, antibody typing and logistics regression analysis of 1111 physical examination people in plateau area
10.3969/j.issn.1006-2483.2024.02.012
- VernacularTitle:1111例高原地区健康体检人群Hp感染率、抗体分型及logistics回归分析
- Author:
Ying CUI
1
;
Ning JIN
1
;
Xiaoning LIU
1
;
Mei GONG
1
;
Wenjia WU
1
Author Information
1. Department of Laboratory Medicine ,The 2nd Affiliated Hospital of Chengdu Medical College , Nuclear Industry 416 Hospital , Chengdu , Sichuan 610000 , China
- Publication Type:Journal Article
- Keywords:
Plateau area;
Physical examination people;
Helicobacter pylori infection;
Antibody typing;
Logistics regression analysis
- From:
Journal of Public Health and Preventive Medicine
2024;35(2):53-56
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the Helicobacter pylori (Hp) infection rate and antibody typing of 1111 physical examination people in plateau area, and to analyze the risk factors of Hp infection by logistics regression analysis. Methods 1111 healthy people with physical examination in plateau area from January 2022 to December 2022 were selected as the research subjects. The Hp infection rate and antibody typing were calculated, and the risk factors of Hp infection were analyzed by logistics regression analysis. Results The Hp infection rate of physical examination people in plateau area was 62.47% (694/1 111). The infection rate of type I HP in infected patients was higher than that of type Ⅱ HP(75.50% vs 24.50%) (χ2=361.141, P<0.001). The AUC of CagA in the diagnosis of Hp infection was higher than that of antibody VacA or Ure positive diagnosis alone (Z=6.740, 7.608, P<0.001). The proportions of people with male gender, often eating pickled or barbecued foods, history of chronic gastric disease and family members living together≥4 in infected group were higher than those in uninfected group (χ2=4.418, 8.708, 16.565, 32.583, P=0.036, 0.003, <0.001, <0.001) while the proportion of people with regular garlic consumption was lower than that in uninfected group (χ2=5.153, P=0.023). Often eating pickled or barbecued foods [OR (95%CI)=2.038 (1.049-3.961)], history of chronic gastric disease [OR(95%CI)=1.706 (1.132-2.569)] and family members living together≥4 [OR (95%CI)=1.857 (1.135-3.037)] were risk factors of Hp infection, and regular garlic consumption [OR (95%CI)=0.559 (0.346-0.903)] was a protective factor (P=0.036, 0.011, 0.014, 0.018). Conclusion The Hp infection rate and antibody Ure positive rate are higher in physical examination people in plateau area, and chronic gastric disease history and often eating pickled or barbecued foods are risk factors of Hp infection.
