Advances in Research on Immune Checkpoint Inhibitors-related Enterocolitis and Gut Microbiota
10.3969/j.issn.1008-7125.2020.07.009
- Author:
Zhi HE
1
;
Feng YE
1
;
Guoxin ZHANG
1
Author Information
1. Department of Gastroenterology, The First Affiliated Hospital of Nanjing Medical University
- Publication Type:Journal Article
- Keywords:
Drug Toxicity;
Enteritis;
Fecal Microbiota Transplantation;
Gut Microbiota;
Immune Checkpoint Inhibitors
- From:
Chinese Journal of Gastroenterology
2020;25(7):424-427
- CountryChina
- Language:Chinese
-
Abstract:
With the application of immune checkpoint inhibitors (ICIs) in the treatment of tumor, the immune-related adverse events often affect the treating process, and the ICI-related enterocolitis is the most common and severe one. Studies on fecal microbiota transplantation revealed that reconstruction of gut microbiota is of great value in the treatment of tumor and other diseases. This article reviewed the advances in research on ICI-related enterocolitis and the role of gut microbiota in tumor immunotherapy.
